Services
Welcome to our service offerings.
In-house we have three mass spectrometers:
- 1290-6490 UHPLC-high end Agilent QqQ-MS
- UPLC-QqQ Waters Acquity- AB Sciex Api4000
- Agilent 6125 LC-DAD-MSD
Access via our collaboration with RadboudUMC and ErasmusMC to high resolution mass spectrometers QTOF and Orbitrap.
Together with our broad knowledge in Pharmacy and Chemistry enable these us to offer a variety of analyses:
Characterization of novel compounds & proteins
- Compound mass identification
- Intact protein analysis by QTOF high resolution mass spectrometry
- Antibody – drug conjugate (ADC) ratio determination
- Protein glycosylation analysis as Critical Quality Attribute (CQA) on therapeutic antibodies
- High-pressure Size Exclusion Chromatography (HP-SEC)
- Stability studies of small molecules and proteins
- Monosaccharide analysis
- RNA characterization
- Peptide mapping or protein sequencing
- Impurity analyses
- SDS-PAGE gel electrophoresis